{"Id":"024b5b0c-b62c-48a6-91b4-6473aa5b1998","CanonicalId":"GSE124742","Url":"https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE124742","Name":"Single-cell patch-seq of human pancreatic islet cells","Description":"Combined single-cell RNA-seq and electrophysiological profiling of human pancreatic islet cells (pancreas patch-seq) to link transcriptomic phenotypes of islet cells to their physiologic properties. The dataset contains 1,369 pancreas patch-seq cells from human donors (nondiabetic and type II diabetes), 348 cryopreserved patch-seq cells (nondiabetic and type I diabetes) and 3,518 FACS islet cells from the same donors. In total cells from 18 nondiabetic , 7 T2D donors, 3 T1D (cryopreserved) and 3 nondiabetic donors (cryopreserved) were used. Single-cell RNA libraries were done using SmartSeq2.","ResourceType":"Dataset","ParentResourceType":null,"DefiningManuscriptId":"32302527","Publications":[],"Contributors":[{"Role":{"CanonicalId":"hirn-cv-ResourceRole-producer","Url":"resources.hirnetwork.org/api/v1/CV/","Name":"Producer","OntologyId":"HIRN"},"HirnUserId":"xiaoqing_dai@hirnetwork.org","FirstName":"XiaoQing","LastName":"Dai","EmailAddress":"xdai@ualberta.ca","Organization":"University of Alberta","Consortia":[]},{"Role":{"CanonicalId":"hirn-cv-ResourceRole-producer","Url":"resources.hirnetwork.org/api/v1/CV/","Name":"Producer","OntologyId":"HIRN"},"HirnUserId":"seung_kim@hirnetwork.org","FirstName":"Seung","LastName":"Kim","EmailAddress":"seungkim@stanford.edu","Organization":"Stanford University","Consortia":["CTAR","HPAC"]},{"Role":{"CanonicalId":"hirn-cv-ResourceRole-producer","Url":"resources.hirnetwork.org/api/v1/CV/","Name":"Producer","OntologyId":"HIRN"},"HirnUserId":"quake@hirnetwork.org","FirstName":"Stephen","LastName":"Quake","EmailAddress":"quake@stanford.edu","Organization":"Stanford University","Consortia":[]},{"Role":{"CanonicalId":"hirn-cv-ResourceRole-producer","Url":"resources.hirnetwork.org/api/v1/CV/","Name":"Producer","OntologyId":"HIRN"},"HirnUserId":"patrick_macdonald@hirnetwork.org","FirstName":"Patrick","LastName":"MacDonald","EmailAddress":"pem@ualberta.ca","Organization":"University of Alberta","Consortia":["HPAC"]}],"Vendor":{"id":null,"Name":"","Url":""},"VendorResourceName":"","VendorResourceUrl":"","VendorCatNumber":"","VendorLotNumber":"","DateCreated":"2021-05-04T00:15:08.3875356+00:00","DateModified":"2022-07-01T03:37:21.3603575+00:00","VersionId":"9","ModelVersion":"4.0","DatasetData":{"DatasetType":{"CanonicalId":"http://purl.bioontology.org/ontology/NCIT?conceptid=http%3A%2F%2Fncicb.nci.nih.gov%2Fxml%2Fowl%2FEVS%2FThesaurus.owl%23C153189","Url":"http://purl.bioontology.org/ontology/NCIT?conceptid=http%3A%2F%2Fncicb.nci.nih.gov%2Fxml%2Fowl%2FEVS%2FThesaurus.owl%23C153189","Name":"Transcriptomics Dataset","OntologyId":"NCIT"},"ExperimentDesign":{"CanonicalId":"","Url":"","Name":"","OntologyId":""},"BiosampleCharacteristics":[{"CanonicalId":"http://purl.obolibrary.org/obo/NCBITaxon_9606","Url":"http://purl.obolibrary.org/obo/NCBITaxon_9606","Name":"Homo sapiens","OntologyId":"ERO"}],"BiosampleType":[{"CanonicalId":"http://purl.obolibrary.org/obo/UBERON_0000006","Url":"http://purl.obolibrary.org/obo/UBERON_0000006","Name":"islet of Langerhans","OntologyId":"CL"}],"TechnologyType":{"CanonicalId":"http://purl.obolibrary.org/obo/OBI_0001271","Url":"http://purl.obolibrary.org/obo/OBI_0001271","Name":"RNA-seq assay","OntologyId":"OBI"}}}