{"Id":"2d79d188-daae-11e7-9bda-db9b5c1a3f04","CanonicalId":"RRID:SAMN47586590","Url":"","Name":"Diabetes-causing CD4 T cell clones from NOD mice","Description":"Isolated from non-obese diabetic (NOD) mice. These pathogenic CD4 T cells target peptide ligands that are formed by covalent crosslinking of proinsulin peptides to other peptides present in beta-cell secretory granules.","ResourceType":"PrimaryCell","ParentResourceType":"Cell","DefiningManuscriptId":"PMID26912858","Publications":[],"Contributors":[{"Role":{"CanonicalId":"hirn-cv-ResourceRole-producer","Url":"resources.hirnetwork.org/api/v1/CV/","Name":"Producer","OntologyId":"HIRN"},"HirnUserId":"rita_bottino@hirnetwork.org","FirstName":"Rita","LastName":"Bottino","EmailAddress":"RBottino@wpahs.org","Organization":"Allegheny Health Network","Consortia":["CTAR"]},{"Role":{"CanonicalId":"hirn-cv-ResourceRole-producer","Url":"resources.hirnetwork.org/api/v1/CV/","Name":"Producer","OntologyId":"HIRN"},"HirnUserId":"al_powers@hirnetwork.org","FirstName":"Al","LastName":"Powers","EmailAddress":"al.powers@vanderbilt.edu","Organization":"Vanderbilt  University","Consortia":["CTAR","CBDS","HPAP","OPP"]},{"Role":{"CanonicalId":"hirn-cv-ResourceRole-producer","Url":"resources.hirnetwork.org/api/v1/CV/","Name":"Producer","OntologyId":"HIRN"},"HirnUserId":"david_harlan@hirnetwork.org","FirstName":"David","LastName":"Harlan","EmailAddress":"David.Harlan@umassmemorial.org","Organization":"University of Massachusetts Medical School","Consortia":["CMAI"]},{"Role":{"CanonicalId":"hirn-cv-ResourceRole-producer","Url":"resources.hirnetwork.org/api/v1/CV/","Name":"Producer","OntologyId":"HIRN"},"HirnUserId":"sally_kent@hirnetwork.org","FirstName":"Sally","LastName":"Kent","EmailAddress":"Sally.Kent@umassmed.edu","Organization":"University of Massachusetts Medical School","Consortia":["OPP"]}],"Vendor":{"id":null,"Name":"","Url":""},"VendorResourceName":"","VendorResourceUrl":"","VendorCatNumber":"","VendorLotNumber":"","DateCreated":"2017-12-06T17:52:08+00:00","DateModified":"2022-07-01T03:36:32.7335667+00:00","VersionId":"4","ModelVersion":"4.0","CellData":{"CellType":[{"CanonicalId":"http://purl.obolibrary.org/obo/CL_0000624","Url":"http://purl.obolibrary.org/obo/CL_0000624","Name":"CD4-positive, alpha-beta T cell","OntologyId":"CL"}],"CellMarkers":[],"CultureConditions":"","Species":[{"CanonicalId":"http://purl.bioontology.org/ontology/NCBITAXON/10090","Url":"http://purl.bioontology.org/ontology/NCBITAXON/10090","Name":"Mus musculus","OntologyId":"NCBITAXON"}],"Sex":null,"Ethnicity":[],"PrimaryDisease":{"CanonicalId":"http://purl.obolibrary.org/obo/DOID_9744","Url":"http://purl.obolibrary.org/obo/DOID_9744","Name":"type 1 diabetes mellitus","OntologyId":"DOID"},"SecondaryDisease":{"CanonicalId":"","Url":"","Name":"","OntologyId":""},"SpecimenState":{"CanonicalId":"","Url":"","Name":"","OntologyId":""},"AgeAtSampling":"","AgeAtDiseaseOnset":"","AgeAtDeath":"","TransientModifications":"","DifferentiatedCellData":{"PrecursorCell":"","GeneticModifications":"","PassageNumber":""},"OtherCellLineData":{"GrowthProperties":"","PrecursorLineName":"","InductionMethod":"","PassageNumber":"","AuthenticationMethod":"","AuthenticationFrequency":"","AuthenticationResult":""},"PrimaryCellData":{"SourceTissue":[],"InductionMethod":""},"StemCellData":{"PassageNumber":"","PassagingMethod":"","InductionMethod":"","KaryotypingResult":"","PassageLastKaryotyping":"","ReprogrammingVectorType":"","ReprogrammingGeneCombo":"","OtherReprogrammingConditions":""}}}