{"Id":"526c8bdf-168f-475f-9fa3-bc783ae8852e","CanonicalId":"","Url":"https://pubmed.ncbi.nlm.nih.gov/28974764/","Name":"Magnetic bead assay for mechanical stimulation of endothelial cells","Description":"The assay mechanically stimulates endothelial cells using thrombin-coated magnetic beads that are manipulated by rare earth magnets. It can more specifically study the effects of mechanical stimulation compared to using soluble signaling factors. Moreover, somewhat variable static and dynamic stimulation studies can be implemented by adjusting the placement and rotation speeds of the magnets.","ResourceType":"AssayTechnology","ParentResourceType":"Technology","DefiningManuscriptId":"PMID28974764","Publications":[],"Contributors":[{"Role":{"CanonicalId":"hirn-cv-ResourceRole-producer","Url":"resources.hirnetwork.org/api/v1/CV/","Name":"Producer","OntologyId":"HIRN"},"HirnUserId":"steven_george@hirnetwork.org","FirstName":"Steven","LastName":"George","EmailAddress":"scg@seas.wustl.edu","Organization":"University of California, Davis","Consortia":["CHIB"]}],"Vendor":{"id":null,"Name":"","Url":""},"VendorResourceName":"","VendorResourceUrl":"","VendorCatNumber":"","VendorLotNumber":"","DateCreated":"2019-04-26T01:22:19.1197314+00:00","DateModified":"2022-07-01T03:35:02.3664054+00:00","VersionId":"2","ModelVersion":"4.0","TechnologyData":{"Dependencies":[],"AssayTechnologyData":{"BioSampleType":[{"CanonicalId":"http://purl.bioontology.org/ontology/NCBITAXON/9606","Url":"http://purl.bioontology.org/ontology/NCBITAXON/9606","Name":"human","OntologyId":"NCBITAXON"},{"CanonicalId":"http://purl.bioontology.org/ontology/NCBITAXON/10090","Url":"http://purl.bioontology.org/ontology/NCBITAXON/10090","Name":"mouse","OntologyId":"NCBITAXON"}],"CellsTestedWith":[{"CanonicalId":"http://purl.obolibrary.org/obo/CL_0002618","Url":"http://purl.obolibrary.org/obo/CL_0002618","Name":"endothelial cell of umbilical vein","OntologyId":"CL"},{"CanonicalId":"http://purl.obolibrary.org/obo/CL_0002553","Url":"http://purl.obolibrary.org/obo/CL_0002553","Name":"fibroblast of lung","OntologyId":"CL"}],"AssayTarget":{"CanonicalId":"","Url":"","Name":"","OntologyId":""},"AssayCategory":{"CanonicalId":"http://purl.obolibrary.org/obo/ERO_0000401","Url":"http://purl.obolibrary.org/obo/ERO_0000401","Name":"cellular assay","OntologyId":"ERO"},"TechnologyType":{"CanonicalId":"","Url":"","Name":"","OntologyId":""},"TechnologyPlatform":"","CompatibleTools":[{"CanonicalId":"http://purl.obolibrary.org/obo/ERO_0000462","Url":"http://purl.obolibrary.org/obo/ERO_0000462","Name":"orbital shaker","OntologyId":"ERO"}]},"DeviceEquipmentTechnologyData":{"CompatibleTools":[],"CellsTestedWith":[],"Placeholder":"Test"},"ServiceTechnologyData":{"CellsTestedWith":[],"Placeholder":"test"},"CodePipelineTechnologyData":{"Placeholder":"Test"}}}