{"Id":"5cc72c64-cc09-11e7-b8c5-c5f835ee25ab","CanonicalId":"GSE70901","Url":"https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE70901","Name":"Gene expression of stem cell-derived beta-cells from T1D patients","Description":"Differentiated cells were sorted and processed for RNA isolation using the MARIS protocol published previously (PMID: 24516164). Human induced pluripotent stem cell (hiPSC) line were differentiated into SC-beta cells or dysfunctional, polyhormonal cells (PH). Four biological replicates were assessed with differentiation to both SC-beta and PH cells. Those data were normalized together with and compared to existing, previously published data from Hrvatin et al. (PMID: 24516164) and Pagliuca et al. (PMID: 25303535) from human islet-derived insulin+ cells, undifferentiated HUES8 hES cells, SC-beta cells derived from HUES8 and PH cells derived from HUES8 according to previously published protocols.","ResourceType":"Dataset","ParentResourceType":null,"DefiningManuscriptId":"PMID27163171","Publications":[],"Contributors":[],"Vendor":{"id":null,"Name":"","Url":""},"VendorResourceName":"","VendorResourceUrl":"","VendorCatNumber":"","VendorLotNumber":"","DateCreated":"2017-11-18T02:37:04+00:00","DateModified":"2022-07-01T03:37:21.3171041+00:00","VersionId":"4","ModelVersion":"4.0","DatasetData":{"DatasetType":{"CanonicalId":"http://purl.bioontology.org/ontology/NCIT?conceptid=http%3A%2F%2Fncicb.nci.nih.gov%2Fxml%2Fowl%2FEVS%2FThesaurus.owl%23C153189","Url":"http://purl.bioontology.org/ontology/NCIT?conceptid=http%3A%2F%2Fncicb.nci.nih.gov%2Fxml%2Fowl%2FEVS%2FThesaurus.owl%23C153189","Name":"Transcriptomics Dataset","OntologyId":"NCIT"},"ExperimentDesign":{"CanonicalId":"","Url":"","Name":"","OntologyId":""},"BiosampleCharacteristics":[{"CanonicalId":"http://purl.obolibrary.org/obo/NCBITaxon_9606","Url":"http://purl.obolibrary.org/obo/NCBITaxon_9606","Name":"Homo sapiens","OntologyId":"ERO"}],"BiosampleType":[{"CanonicalId":"http://purl.obolibrary.org/obo/BCGO_0000014","Url":"http://purl.obolibrary.org/obo/BCGO_0000014","Name":"functional beta cell like cell","OntologyId":"BCGO"}],"TechnologyType":{"CanonicalId":"http://purl.obolibrary.org/obo/OBI_0001463","Url":"http://purl.obolibrary.org/obo/OBI_0001463","Name":"transcription profiling by array assay","OntologyId":"OBI"}}}