{"Id":"8a746892-33bf-449f-9874-104366439f97","CanonicalId":"GSE145126","Url":"https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE145126","Name":"Microarray analysis of c-Jun/JunB knockout mice treated with dithranol","Description":"Ears of c-Jun/JunB knockout mice were topically treated with dithranol. Mice carrying floxed alleles for the JunB and c-Jun locus and expressing the K5-CreERT transgene received consecutive i.p. injections of tamoxifen for a period of 5 days, leading to deletion of both genes in the epidermis by inducible Cre-recombinase activity. One week after the last injection, psoriasis-like lesions on the ears were treated daily with vehicle (Vaseline) or dithranol in series of increasing concentrations.","ResourceType":"Dataset","ParentResourceType":null,"DefiningManuscriptId":"PMID35228745","Publications":[],"Contributors":[{"Role":{"CanonicalId":"hirn-cv-ResourceRole-contact","Url":null,"Name":"Contact","OntologyId":null},"HirnUserId":"klaus_kaestner@hirnetwork.org","FirstName":"Klaus","LastName":"Kaestner","EmailAddress":"kaestner@mail.med.upenn.edu","Organization":"University of Pennsylvania","Consortia":["CTAR","HPAC","OPP","CBDS"]},{"Role":{"CanonicalId":"hirn-cv-ResourceRole-contact","Url":null,"Name":"Contact","OntologyId":null},"HirnUserId":"daniel_traum@hirnetwork.org","FirstName":"Daniel","LastName":"Traum","EmailAddress":"traum@pennmedicine.upenn.edu","Organization":"University of Pennsylvania","Consortia":[]}],"Vendor":{"id":null,"Name":"","Url":""},"VendorResourceName":"","VendorResourceUrl":"","VendorCatNumber":"","VendorLotNumber":"","DateCreated":"2022-03-09T19:52:28.4791381+00:00","DateModified":"2022-07-01T03:36:48.9953788+00:00","VersionId":"2","ModelVersion":"4.0","DatasetData":{"DatasetType":{"CanonicalId":"http://purl.bioontology.org/ontology/NCIT?conceptid=http%3A%2F%2Fncicb.nci.nih.gov%2Fxml%2Fowl%2FEVS%2FThesaurus.owl%23C20085","Url":"http://purl.bioontology.org/ontology/NCIT?conceptid=http%3A%2F%2Fncicb.nci.nih.gov%2Fxml%2Fowl%2FEVS%2FThesaurus.owl%23C20085","Name":"Proteomics Dataset","OntologyId":"NCIT"},"ExperimentDesign":{"CanonicalId":"http://www.ebi.ac.uk/efo/EFO_0001032","Url":"http://www.ebi.ac.uk/efo/EFO_0001032","Name":"transcription profiling","OntologyId":"EFO"},"BiosampleCharacteristics":[{"CanonicalId":"http://purl.obolibrary.org/obo/NCBITaxon_10090","Url":"http://purl.obolibrary.org/obo/NCBITaxon_10090","Name":"Mus musculus","OntologyId":"ERO"}],"BiosampleType":[{"CanonicalId":"http://purl.obolibrary.org/obo/UBERON_0000479","Url":"http://purl.obolibrary.org/obo/UBERON_0000479","Name":"tissue","OntologyId":"ERO"}],"TechnologyType":{"CanonicalId":"http://purl.obolibrary.org/obo/OBI_0400147","Url":"http://purl.obolibrary.org/obo/OBI_0400147","Name":"microarray","OntologyId":"OBI"}}}