Resource Type
Technology / AssayTechnology
Resource Name

Electrochemical-based sensor assay for differentiating DNA polymorphisms
Canonical Identifier
Description
A proof-of-concept assay for detection of DNA polymorphisms based on exploiting the catalytic reaction between methylene blue (MB) covalently linked to surface-bound nucleic acid and freely diffusing ferricyanide (Fe(CN)63–) to improve specificity and sensitivity of DNA polymorphism detection. The sensor can achieve a 20 pM limit of detection.
Contributors
NameOrganizationConsortiumContact
Ryan WhiteUniversity of CincinnatiCHIB Contact
Tags or Keywords
Defining Manuscript Identifier
PMID33305566


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