Resource Type
Technology / AssayTechnology
Resource Name

Assay using reaction-based probes preferentially targeting pancreatic beta-cells and beta-like cells
Canonical Identifier
Description
The assay uses an engineered reaction-based probe, diacetylated Zinpyr1 (DA-ZP1), that can be used to image pancreatic beta-cells and beta-like cells derived from human pluripotent stem cells. It exploits the high intracellular zinc concentration of beta-cells to induce a fluorescence signal in cells after administration of DA-ZP1.
Contributors
NameOrganizationConsortiumContact
Bridget WagnerBroad InstituteCTAR Contact
Amit ChoudharyBroad InstituteCTAR Contact
Rohit KulkarniJoslin Diabetes CenterCBDS, CTAR Contact
Tags or Keywords
Defining Manuscript Identifier
PMID33514654


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