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Transcript data of HNF1a mutants derived from hESC lines

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CRISPR-Cas9 was used to generate HNF1a mutants (+/- and -/-) in human embryonic stem cell lines and used an in vitro differentiation system to study pancreatic beta cell differentiation and subsequent function of the derivative beta cells.
Contributors
NameOrganizationConsortiumContact
Siddharth KishoreUniversity of PennsylvaniaCHIB Contact
Karla LeavensCHIB Contact
Christine YoonBoston University Contact
Chris ChenBoston UniversityCHIB Contact
Marcela BrissovaVanderbilt UniversityCTAR, CBDS, HPAC Contact
Paul GadueCHIB Contact
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