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RNA-seq of stem cell derived liver and pancreas organoids

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We systematically probed which cell types are permissive to SARS-CoV-2 infection. Transcriptomic analysis following SARS-CoV-2 infection of hPSC-derived pancreatic and lung organoids revealed upregulation of chemokines but not type I/III interferon signaling, similar to what was seen in primary human COVID-19 pulmonary infection.
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Ali NajiUniversity of PennsylvaniaHPAC, CBDS, CHIB Contact
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