Resource Type
Technology / DeviceEquipmentTechnology
Resource Name

Engineered peri-islet basement membrane-like structures
Canonical Identifier
Description
Engineered ECM networks can be useful for improved islet mimetic systems. The method constructs a peri-islet ECM on the surfaces of isolated rat and human islets by the co-assembly from solution of laminin, nidogen and collagen IV proteins. Successful deposition of contiguous peri-islet ECM networks was confirmed by immunofluorescence, western blot, and transmission electron microscopy.
Contributors
NameOrganizationConsortiumContact
Cherie StablerUniversity of FloridaCHIB Contact
Holger RussUniversity of Colorado, DenverCBDS, OPP Contact
Defining Manuscript Identifier
PMID33895491


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