Resource Type
ModelOrganism
Resource Name

NOD-scid

Canonical Identifier
Alternative/Secondary Identifiers
CanonicalIdName
NOD.CB17-Prkdcscid/J
Description
From Jackson Labs: Mice homozygous for the severe combined immune deficiency spontaneous mutation Prkdcscid, commonly referred to as scid, are characterized by an absence of functional T cells and B cells, lymphopenia, hypogammaglobulinemia, and a normal hematopoietic microenvironment. Prkdcscid mice accept allogeneic and xenogeneic grafts making them an ideal model for cell transfer experiments. In general, Prkdcscid leakiness is low on the NOD/ShiLtSz genetic background.
Tags or Keywords
Defining Manuscript Identifier
Related Resources
Canonical IdentifierNameResource Type
Methylation profiling of insulin DNA in response to proinflammatory cytokines during the progression of autoimmune diabetes in NOD miceDataset
RRID:IMSR_JAX:001976NODModelOrganism


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genotyping

Publications
PMID31087105 HIRN SUPPORTED

Contacts
Peter Buchwald
humanized mouse

Publications
PMID36928765 HIRN SUPPORTED

Contacts
Mark Huising
humanized mouse

Publications
PMID28190773 HIRN SUPPORTED

Contacts
Kevan Herold
humanized mouse

Publications
PMID26773144 HIRN SUPPORTED

Contacts
Alexei Savinov
Species
Strain Category
Strain Genetic Background
NOD/ShiLtSz
Authentication Method
Genotype by PCR


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