Resource Type
ModelOrganism
Resource Name

Pdx1-tTA
Canonical Identifier
Description
Strain allows for transgene induction of p16 using the Pdx1-tTA driver (tet off). These mice are deficient in one allele of the Pdx1 gene, mimicking a monogenic familial form of diabetes, maturity-onset diabetes of the young (MODY) 4.
Tags or Keywords
Defining Manuscript Identifier
PMID26950362
Related Resources
Canonical IdentifierNameResource Type
CDK4+/lsl-R24CModelOrganism
Ins2-rtTAModelOrganism
Ins2-rtTA;tet-p16ModelOrganism
Ins2-rtTA;tet-p16;tet-GFPModelOrganism
MIP-CreER;CDK4+/R24CModelOrganism
RRID:IMSR_NCIMR:01XE4p16-deficientModelOrganism
Pdx1-tTA;tet-p16ModelOrganism
GSE76992RNA-seq of p16ink4a-expressing pancreatic beta-cellsDataset
tet-GFPModelOrganism
tet-inducible p16Ink4a (tet-p16)ModelOrganism


Have you used this resource?


Species
Strain Category
Strain Genetic Background
mixed ICR
Authentication Method
Genotype by PCR



.