Resource Type
ModelOrganism
Resource Name

NSG-DTR
Canonical Identifier
Description
Strain has two autosomal copies of the RIP-DTR transgene (from parent NGS RIP-DTR strain) backcrossed onto the NSG background. NSG-DTR is a severely immunodeficient mouse with excellent xenograft tolerance, in which diphtheria toxin (DT) injection can ablate mouse beta-cells.
Contributors
NameOrganizationConsortiumContact
Chunhua DaiVanderbilt UniversityCTAR Contact
Greg PoffenbergerVanderbilt University Contact
Dale GreinerUniversity of Massachusetts Medical SchoolCMAI Contact
Pedro HerreraUniversity of GenevaCTAR, CBDS Contact
Leonard ShultzThe Jackson LaboratoryCMAI Contact
Al PowersVanderbilt UniversityCTAR, CBDS, HPAP, OPP Contact
Tags or Keywords
Defining Manuscript Identifier
PMID27064285
Related Resources
Canonical IdentifierNameResource Type
(B6;129 Sv)-Glut4+/-ModelOrganism
NSG RIP-DTRModelOrganism
NSG-Glut4ModelOrganism
NSG-obModelOrganism


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Species
Strain Category
Strain Genetic Background
NOD/ShiLtJ
Authentication Method
Genotype by PCR



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