Resource Type
ModelOrganism
Resource Name

NSG-Ab 0 DR4

Canonical Identifier
Alternative/Secondary Identifiers
CanonicalIdName
NOD.Cg-Prkdcscid Il2rgtm1Wjl H2-Ab1tm1GruTg(HLA-DRB1)31Dmz/SzJ
Description
From Jackson Labs: These compound mutant NSG-Abo DR4 mice lack expression of the murine Prkdc gene, the X-linked Il2rg gene, and MHC class II while expressing the human leukocyte antigen DR4 gene. These mice may be useful for targeting human CD4+ T cells in transplantation studies in the absence of xeno-GVHD.
Contributors
NameOrganizationConsortiumContact
Michael BrehmUniversity of Massachusetts Medical SchoolCMAI Contact
Leonard ShultzThe Jackson LaboratoryCMAI Contact
Dale GreinerUniversity of Massachusetts Medical SchoolCMAI Contact
Teresa DiLorenzoAlbert Einstein College of Medicine Contact
Tags or Keywords
Defining Manuscript Identifier
Related Resources
Canonical IdentifierNameResource Type
Clone 164 TCR-transduced CD4+ T cell linePrimaryCell


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Species
Strain Category
Authentication Method
Genotype by PCR


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