Resource Type
ModelOrganism
Resource Name

BKS db (db/db)

Canonical Identifier
Alternative/Secondary Identifiers
CanonicalIdName
BKS.Cg-+Leprdb/+Leprdb/OlaHsd
Description
(The db/db mice from Envigo is comparable to Jackson strain #000642.) A model for type 2 diabetes; hyperglycemic; proteinuria; glycosuria; Leptin receptor deficient; obesity expressed at 4-5 weeks of age; hyperinsulinemia despite severe depletion of pancreatic islet insulin-producing B-cells; hyperglycemia develops at 4-8 weeks of age.
Vendor
Tags or Keywords
Defining Manuscript Identifier
Related Resources
Canonical IdentifierNameResource Type
betaPAX6ModelOrganism
RRID:IMSR_JAX:024709MIP-CreERModelOrganism
RRID:IMSR_JAX:28032Pax6fl/flModelOrganism
RRID:IMSR_JAX:006148R26R-EYFPModelOrganism
GSE87530Whole genome map of PAX6 bound sites from Min6 and EndoC cells (n=3); whole genome map of histones enriched for H3K9ac modification from pancreatic beta cells of Bl6 miceDataset


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Species
Strain Category
Strain Genetic Background
BKS
Authentication Method
Genotype by PCR


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