Resource Type
ModelOrganism
Resource Name

Gcg-CreERT2
Canonical Identifier
Description
Expresses CreERT2 in pancreatic alpha-cells and enteroendocrine L-cells without disrupting preproglucagon gene expression. See description for the derived Gcg-CreERT2;Rosa26-LSL-YFP strain.
Contributors
NameOrganizationConsortiumContact
Amanda AckermannUniversity of PennsylvaniaCTAR Contact
Klaus KaestnerUniversity of PennsylvaniaCTAR, HPAP, OPP, CBDS Contact
Tags or Keywords
Defining Manuscript Identifier
PMID28271030
Related Resources
Canonical IdentifierNameResource Type
RRID:AB_641026Anti-Glucagon (FL-180) AntibodyAntibody
RRID:AB_86637Anti-INSULIN Polyclonal Antibody, UnconjugatedAntibody
Gcg-CreERT2;Rosa26-LSL-YFPModelOrganism
RRID:AB_305643Goat Anti-GFP (Green Fluorescent Protein) Polyclonal Antibody, UnconjugatedAntibody
RRID:AB_10806983Rabbit anti-Cre AntibodyAntibody


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Species
Strain Category
Genetic Modifications
CRISPR-Cas9 used to insert IRES-CreERT2 sequence into the 3' UTR of the Glucagon (Gcg) locus
Authentication Method
Genotype by PCR



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