HIRN Resource Browser - ModelOrganism

Resource Type

ModelOrganism

Resource Name

NSG-Hc1

Canonical Identifier

Alternative/Secondary Identifiers

CanonicalId	Name

NOD.Cg-Hc¹ Prkdc^scid Il2rg^tm1Wjl/SzJ

Description

From Jackson Labs: NSG-Hc1 mice express an intact hemolytic complement system on the immunodeficient NOD scid gamma (NSG) background. This strain may be useful to compare complement-dependent and complement-independent cytotoxic activity mediated by therapeutic monoclonal antibodies.

Contributors

Name	Organization	Consortium	Contact

Michael Brehm	University of Massachusetts Medical School	CMAI	Contact
Dale Greiner	University of Massachusetts Medical School	CMAI	Contact
Leonard Shultz	The Jackson Laboratory	CMAI	Contact

Tags or Keywords

reviewed_humanized_mice

Defining Manuscript Identifier

PMID28390927

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Publications

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Notes

Species	Mus musculus
Sex
Primary Disease
Secondary Disease
Strain Category	Congenic Strain, Targeted Mutation, Spontaneous Mutation
Strain Genetic Background
Genetic Modifications
Authentication Method	Genotype by PCR
Authentication Frequency
Authentication Result