HIRN Resource Browser - ModelOrganism

Resource Type

ModelOrganism

Resource Name

RIP-DTR

Canonical Identifier

Alternative/Secondary Identifiers

CanonicalId	Name

NOD.Cg-Prkdc^scid Il2rg^tm1Wjl Tg(Ins2-HBEGF)6832Ugfm/SzJ

Description

From Jackson Labs: Diphtheria toxin treatment ablates all pancreatic beta cells in these NSG RIP-DTR mice. This strain is useful for engraftment of human pancreatic islets, and studies related to islet transplantation.

Vendor

The Jackson Laboratory

Vendor Catalog Number

027976

Tags or Keywords

Defining Manuscript Identifier

PMID28119131

Related Resources

Canonical Identifier	Name	Resource Type

	Dnmt1fl/fl	ModelOrganism
	Ezh2fl/fl	ModelOrganism
	Glucagon-rtTA	ModelOrganism
	Somatostatin-Cre	ModelOrganism
	TetO-Cre	ModelOrganism

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genotyping

Publications
PMID27092792 HIRN SUPPORTED

Contacts
Fabrizio Thorel
Al Powers
Pedro Herrera

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Notes

Species	Mus musculus
Sex
Primary Disease
Secondary Disease
Strain Category	Congenic Strain, Transgenic Strain, Targeted Mutation, Spontaneous Mutation
Strain Genetic Background
Genetic Modifications
Authentication Method	Genotype by PCR
Authentication Frequency
Authentication Result