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Search Results for: Chengyang Liu returned 13 results
Human/Mouse Somatostatin Antibody RRID:AB_2722572 |
scRNA-seq of SARS-CoV-2 infected human islets GSE159556 RNA profiles of five total samples of human primary islets from two different donors: two infected with SARS-CoV-2, two mock-infected, and one infected with SARS-CoV-2 and also treated with the small molecule trans-ISRIB. It was observed that SARS-CoV-2 infection promoted transdifferentiation of beta cells, and the small molecule trans-ISRIB counteracted this phenomenon. |
Pancreatic Polypeptide/PP Antibody RRID:AB_2268669 |
Sheep Anti-Human Neurogenin-3 Affinity purified Polyclonal antibody, Unconjugated RRID:AB_2149527 |
HEK293T RRID:CVCL_0063 |
GAPDH RRID:AB_10622025 |
INS-1 832/13 RRID:CVCL_7226 INS-1-derived cell line with robust ATP-sensitive K+ channel-dependent and -independent glucose-stimulated insulin secretion (Hohmeier et al., 2000) |
Mouse Anti-Rat Nkx6.1 Antibody, Unconjugated RRID:AB_532379 |
MIN6 RRID:CVCL_0431 Immortalized beta cell-derived cell line. Comments: MIN6 is not a pure beta cell line but a mixed cell line with other pancreatic endocrine hormones (Nakashima et al., 2009) High passage MIN6 cells have impaired insulin secretion with impaired glucose and lipid oxidation. (Cheng et al., 2012) |
Anti-Ki67 Antibody RRID:AB_443209 |
EndoC-betaH1 RRID:CVCL_L909 Secretes insulin in response to glucose challenge. However, these cells don't produce nitric oxide in reponse to cytokines (IL-1, IFN-gamma, and TNF) in a manner consistent with human islets. They also fail to respond to endoplasmic reticulum stress activators such as thapsigargin. |
Insulin Antibody RRID:AB_2800361 |
Anti-Glucagon Antibody RRID:AB_659831 |
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