Search Results for: juan alvarez returned 35 results

Rabbit Anti-Human EpCAM Polyclonal Antibody, Unconjugated
RRID:AB_1603782

FOXN1 (G-20) antibody
RRID:AB_2231962

Pseudodynamics modeling framework (MATLAB implementation)

A set of scripts to implement pseudodynamics, a mathematical framework that models population distribution shifts across trajectories to quantify selection pressure, population expansion, and developmental potentials. It was applied to time-resolved single-cell RNA-sequencing of T-cell and pancreatic beta cell maturation to characterize proliferation and apoptosis rates and identify key developmental checkpoints, data inaccessible to existing approaches.

Single-cell genomics profiling of the endoderm of the mouse embryonic pharynx [scRNA-seq]
GSE182135

Using human pluripotent stem cells to dissect the molecular basis of human pharyngeal endoderm development [ChIP-seq]
GSE222441

Single-cell RNA sequencing-based CRISPRi screening resolves molecular drivers of early human endoderm development [set 1]
GSE127199

Using human pluripotent stem cells to dissect the molecular basis of human pharyngeal endoderm development [scRNA_RA_titration]
GSE230563

Using human pluripotent stem cells to dissect the molecular basis of human pharyngeal endoderm development [ATAC-seq]
GSE222439

Genome binding/occupancy profiling of V6.5 mouse ESCs after epigenomic modification
GSE64058
Data to validate a novel CRISPR-Cas9 system for epigenomic modification

Single-cell RNA-seq from eight days of mouse thymus development
GSE107910
Samples span from embryonic day 12.5, when the thymus coalesces, until birth. They cover the whole thymus, including mesenchyme, endothelium, epithelium, thymocytes, and other lymphocytes. The dataset also includes Drop-seq data on Rag1-/- embryos and on fetal thymic organ cultures (control and a retinoic acid perturbation).

Single-cell RNA-seq (Drop-seq) of Rag2-/- knockout mouse embryonic thymi
GSE126579
Single-cell RNA-seq (Drop-seq) data from thymi of day 14.5 mouse embryos. The sample includes the whole thymus, including mesenchyme, endothelium, epithelium, thymocytes, and other lymphocytes. The mouse is a Rag2-/- knockout.

Single-cell RNA sequencing-based CRISPRi screening resolves molecular drivers of early human endoderm development [set 2]
GSE127201

Rag1 KO
RRID:IMSR_JAX:002216
From Jackson Labs: Mice homozygous for the Rag1tm1Mom mutation produce no mature T cells or B cells. Their phenotype can be described as a \non-leaky\\\\"\\\" immune deficiency.\\\"\\\"

Using human pluripotent stem cells to dissect the molecular basis of human pharyngeal endoderm development [scRNA-Seq]
GSE221616

CD4+ T cell lines (nPOD6367)

A total of 14 T cell lines grown from individual handpicked islets. Part of a larger collection of 236 islet-infiltrating T cell lines that should be useful for autoantigen reactivity studies.

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