Resource Type
Technology / CodePipelineTechnology
Resource Name

Pseudodynamics modeling framework (MATLAB implementation)

Canonical Identifier
Description
A set of scripts to implement pseudodynamics, a mathematical framework that models population distribution shifts across trajectories to quantify selection pressure, population expansion, and developmental potentials. It was applied to time-resolved single-cell RNA-sequencing of T-cell and pancreatic beta cell maturation to characterize proliferation and apoptosis rates and identify key developmental checkpoints, data inaccessible to existing approaches.
Contributors
NameOrganizationConsortiumContact
Heiko LickertInstitute of Diabetes and Regeneration Research Contact
Rene MaehrUniversity of Massachusetts Medical School Contact
Defining Manuscript Identifier


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population modeling objective


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