Resource Type
Dataset
Resource Name

Next-generation-sequencing (NGS) of ribosome footprintings and poly(A) enriched RNA-seq of mouse insulinoma cell line (MIN6) under acute and chronic endoplasmic reticular stresses
Canonical Identifier
GSE174679
Description
This data was used to examine how adaptation to chronic ER stress enforces pancreatic beta-cell plasticity. A total of 18 samples are available. Design: Mouse insulinoma cells MIN6 treated with 200uM of Cyclopiazonic acid for 1 hour (CPA1) and 18 hours (CPA18); an 18-hour DMSO treatment served as the control (CPA0). Ribo-seq and poly(A) enriched RNA-seq (mRNA-seq) were performed on all. There are three independent biological replications each.
Contributors
NameOrganizationConsortiumContact
Maria Hatzoglou Contact
Chien-Wen Chen Contact
Tags or Keywords
Publications
Name
Adaptation to chronic ER stress enforces pancreatic β-cell plasticity Url


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RNA-Seq
Publications
PMID35941159 HIRN SUPPORTED
Contacts
Klaus Kaestner
Ivan Gerling
Biosample Characteristics
Biosample Type
Technology Type or Sequencing Platform



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