Resource Type
ModelOrganism
Resource Name

C9orf72-/-
Canonical Identifier
Description
Mice harboring loss-of-function mutations in the ortholog of C9ORF72 develop splenomegaly, neutrophilia, thrombocytopenia, increased expression of inflammatory cytokines, and severe autoimmunity.
Contributors
NameOrganizationConsortiumContact
Derrick RossiChildren’s Hospital CorpCMAI Contact
Tags or Keywords
Defining Manuscript Identifier
PMID27412785
Related Resources
Canonical IdentifierNameResource Type
RRID:IMSR_JAX:002014B6 Cd45.1ModelOrganism


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Species
Strain Category
Strain Genetic Background
C57BL/6
Genetic Modifications
LacZ insertion replacing exons 2-6 of the gene C9orf72-/-
Authentication Method
Genotype by PCR



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