HIRN Resource Browser - PrimaryCell - Diabetes-causing CD4 T cell clones from NOD mice

Resource Type

Cell / PrimaryCell

Resource Name

Diabetes-causing CD4 T cell clones from NOD mice

Canonical Identifier

Description

Isolated from non-obese diabetic (NOD) mice. These pathogenic CD4 T cells target peptide ligands that are formed by covalent crosslinking of proinsulin peptides to other peptides present in beta-cell secretory granules.

Contributors

Name	Organization	Consortium	Contact

Rita Bottino	Allegheny Health Network	CTAR	Contact
Al Powers	Vanderbilt University	CTAR, CBDS, HPAP, OPP	Contact
David Harlan	University of Massachusetts Medical School	CMAI	Contact
Sally Kent	University of Massachusetts Medical School	OPP	Contact

Tags or Keywords

Defining Manuscript Identifier

PMID26912858

Related Resources

Canonical Identifier	Name	Resource Type

	CD4 T cells from 19 year old male with 3 years of T1D	PrimaryCell
	CD4 T cells from 20 year-old male with 7 years of T1D	PrimaryCell

Have you used this resource?

Your Email Address

Rating

Usage Contact

Add

Last Name	First Name	Organization	Email

Please add one or more contacts

Publications

Title	Url	HIRN Supported

Please add one or more publications

Notes

Cell Type	CD4-positive, alpha-beta T cell
Cell Markers
Culture Conditions
Donor Species	Mus musculus
Donor Sex
Donor Ethnicity
Donor Primary Disease	type 1 diabetes mellitus
Donor Secondary Disease
Specimen State
Donor Age at Sampling
Donor Age at Disease Onset
Donor Age at Death
Transient Modifications

Source Tissue
Induction Method